Drug interactions
Ciclesonide inhaled + Clarithromycin
Severity: Minor
Ciclesonide inhaled and Clarithromycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Clarithromycin can raise systemic exposure to the active metabolite of ciclesonide. Greater corticosteroid exposure may cause systemic effects such as adrenal suppression, although inhaled ciclesonide is less affected than some other steroids.
What this interaction means in plain words
Ciclesonide inhaled and Clarithromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Clarithromycin inhibits CYP3A4, which contributes to the metabolism of the ciclesonide active metabolite.
What to do
Usually no change is needed for a short antibiotic course. Monitor for corticosteroid systemic effects if the combination is prolonged.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clarithromycin
- Astemizole + Clarithromycin Contraindicated
- Avanafil + Clarithromycin Contraindicated
- Cisapride + Clarithromycin Contraindicated
- Clarithromycin + Colchicine Contraindicated
- Clarithromycin + Conivaptan Contraindicated
- Clarithromycin + Dihydroergotamine Contraindicated
Frequently asked questions
Can I take Ciclesonide inhaled with Clarithromycin?
MediHelp rates the interaction as minor. Ciclesonide inhaled and Clarithromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Clarithromycin can raise systemic exposure to the active metabolite of ciclesonide. Greater corticosteroid exposure may cause systemic effects such as adrenal suppression, although inhaled ciclesonide is less affected than some other steroids.
How serious is the interaction between Ciclesonide inhaled and Clarithromycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Usually no change is needed for a short antibiotic course. Monitor for corticosteroid systemic effects if the combination is prolonged.
What other medicines interact with Clarithromycin?
MediHelp also lists interactions of Clarithromycin with, for example, Astemizole, Avanafil, Cisapride. The full list is on the Clarithromycin page.
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