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Drug interactions

Cinnarizine + Dextroamphetamine

Severity: Minor

Cinnarizine and Dextroamphetamine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cinnarizine is a sedating antihistamine and calcium channel blocker whose drowsiness may be partly offset by dextroamphetamine. Stimulants can mask sedation while impairment persists. Serious harm is not expected.

What this interaction means in plain words

Cinnarizine and Dextroamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cinnarizine belongs to Respiratory; Dextroamphetamine belongs to Central Nervous System.

Evidence level: Low

Why it happens

Opposing central nervous system effects (H1 antagonism versus amphetamine-induced monoamine release).

What to do

No specific action is usually required. Advise caution with driving and watch for tachycardia or agitation.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cinnarizine with Dextroamphetamine?

MediHelp rates the interaction as minor. Cinnarizine and Dextroamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cinnarizine is a sedating antihistamine and calcium channel blocker whose drowsiness may be partly offset by dextroamphetamine. Stimulants can mask sedation while impairment persists. Serious harm is not expected.

How serious is the interaction between Cinnarizine and Dextroamphetamine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is usually required. Advise caution with driving and watch for tachycardia or agitation.

What other medicines interact with Dextroamphetamine?

MediHelp also lists interactions of Dextroamphetamine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Dextroamphetamine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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