Drug interactions
Amobarbital + Cinnarizine
Severity: Moderate
Amobarbital and Cinnarizine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs cause drowsiness, and combining them can deepen sedation and impair coordination and driving ability. Older patients are especially vulnerable to falls.
What this interaction means in plain words
Amobarbital and Cinnarizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amobarbital belongs to Central Nervous System; Cinnarizine belongs to Respiratory.
Why it happens
Additive CNS depression via GABAergic enhancement and antihistaminic sedation.
What to do
Counsel against driving and alcohol, and use the lowest effective doses. Monitor older patients for sedation and falls.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amobarbital
- Amobarbital + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Amobarbital + Doravirine Contraindicated
- Amobarbital + Elbasvir / grazoprevir Contraindicated
- Amobarbital + Isavuconazonium Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amobarbital + Lonafarnib Contraindicated
Other interactions of Cinnarizine
- Alprazolam + Cinnarizine Moderate
- Amitriptyline + Cinnarizine Moderate
- Aripiprazole + Cinnarizine Moderate
- Azelastine-fluticasone + Cinnarizine Moderate
- Azelastine + Cinnarizine Moderate
- Baclofen + Cinnarizine Moderate
Frequently asked questions
Can I take Amobarbital with Cinnarizine?
MediHelp rates the interaction as moderate. Amobarbital and Cinnarizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs cause drowsiness, and combining them can deepen sedation and impair coordination and driving ability. Older patients are especially vulnerable to falls.
How serious is the interaction between Amobarbital and Cinnarizine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel against driving and alcohol, and use the lowest effective doses. Monitor older patients for sedation and falls.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
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