Drug interactions
Ciprofloxacin + Frovatriptan
Severity: Minor
Ciprofloxacin and Frovatriptan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ciprofloxacin may modestly raise frovatriptan exposure because frovatriptan is partly cleared by CYP1A2. Increased triptan effects such as dizziness, nausea or blood pressure elevation are possible but typically mild.
What this interaction means in plain words
Ciprofloxacin and Frovatriptan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ciprofloxacin belongs to Anti Bacterial; Frovatriptan belongs to Central Nervous System.
Why it happens
Ciprofloxacin inhibits CYP1A2, reducing frovatriptan metabolism.
What to do
No routine dose change is usually needed; monitor for triptan adverse effects. Observe the usual maximum daily frovatriptan dose.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Frovatriptan
- Almotriptan + Frovatriptan Contraindicated
- Dihydroergotamine intranasal + Frovatriptan Contraindicated
- Dihydroergotamine + Frovatriptan Contraindicated
- Eletriptan + Frovatriptan Contraindicated
- Ergoloid mesylates + Frovatriptan Contraindicated
- Ergotamine + Frovatriptan Contraindicated
Frequently asked questions
Can I take Ciprofloxacin with Frovatriptan?
MediHelp rates the interaction as minor. Ciprofloxacin and Frovatriptan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ciprofloxacin may modestly raise frovatriptan exposure because frovatriptan is partly cleared by CYP1A2. Increased triptan effects such as dizziness, nausea or blood pressure elevation are possible but typically mild.
How serious is the interaction between Ciprofloxacin and Frovatriptan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is usually needed; monitor for triptan adverse effects. Observe the usual maximum daily frovatriptan dose.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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