Drug interactions
Cisatracurium + Triamcinolone
Severity: Moderate
Cisatracurium and Triamcinolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids given with non-depolarizing neuromuscular blockers have been linked to prolonged weakness and acute myopathy. The risk is greatest with high-dose steroids and extended blockade in critically ill patients.
What this interaction means in plain words
Cisatracurium and Triamcinolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cisatracurium belongs to Musculoskeletal; Triamcinolone belongs to Endocrine.
Why it happens
Additive skeletal muscle toxicity and altered neuromuscular function; the exact mechanism is not fully established.
What to do
Use the shortest possible duration of neuromuscular blockade and the lowest steroid dose. Monitor neuromuscular function and creatine kinase if weakness develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triamcinolone
- Smallpox vaccine live + Triamcinolone Contraindicated
- Triamcinolone + Zoster vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Triamcinolone Major
- Aldesleukin + Triamcinolone Major
- Atazanavir + Triamcinolone Major
- Axicabtagene ciloleucel + Triamcinolone Major
Other interactions of Cisatracurium
Frequently asked questions
Can I take Cisatracurium with Triamcinolone?
MediHelp rates the interaction as moderate. Cisatracurium and Triamcinolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids given with non-depolarizing neuromuscular blockers have been linked to prolonged weakness and acute myopathy. The risk is greatest with high-dose steroids and extended blockade in critically ill patients.
How serious is the interaction between Cisatracurium and Triamcinolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the shortest possible duration of neuromuscular blockade and the lowest steroid dose. Monitor neuromuscular function and creatine kinase if weakness develops.
What other medicines interact with Triamcinolone?
MediHelp also lists interactions of Triamcinolone with, for example, Smallpox vaccine live, Zoster vaccine live, Adenovirus types 4 and 7 live. The full list is on the Triamcinolone page.
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