Drug interactions
Cisplatin + Influenza virus vaccine quadrivalent adjuvanted
Severity: Minor
Cisplatin and Influenza virus vaccine quadrivalent adjuvanted: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cisplatin-induced myelosuppression may blunt the antibody response to inactivated influenza vaccine. The vaccine is not harmful, but protection may be reduced.
What this interaction means in plain words
Cisplatin and Influenza virus vaccine quadrivalent adjuvanted have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Cytotoxic suppression of immune cells may reduce vaccine response.
What to do
Do not withhold the vaccine. Where feasible, vaccinate before chemotherapy or between cycles when counts recover.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cisplatin
- Cidofovir + Cisplatin Contraindicated
- Adefovir + Cisplatin Major
- Adenovirus types 4 and 7 live + Cisplatin Major
- Amikacin + Cisplatin Major
- Amphotericin b deoxycholate + Cisplatin Major
- Amphotericin b + Cisplatin Major
Frequently asked questions
Can I take Cisplatin with Influenza virus vaccine quadrivalent adjuvanted?
MediHelp rates the interaction as minor. Cisplatin and Influenza virus vaccine quadrivalent adjuvanted have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cisplatin-induced myelosuppression may blunt the antibody response to inactivated influenza vaccine. The vaccine is not harmful, but protection may be reduced.
How serious is the interaction between Cisplatin and Influenza virus vaccine quadrivalent adjuvanted?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not withhold the vaccine. Where feasible, vaccinate before chemotherapy or between cycles when counts recover.
What other medicines interact with Cisplatin?
MediHelp also lists interactions of Cisplatin with, for example, Cidofovir, Adefovir, Adenovirus types 4 and 7 live. The full list is on the Cisplatin page.
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