Drug interactions
Clarithromycin + Deferasirox
Severity: Minor
Clarithromycin and Deferasirox: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may lower clarithromycin concentrations, possibly reducing antibacterial effectiveness. The effect is predicted from weak CYP3A4 induction and is probably small.
What this interaction means in plain words
Clarithromycin and Deferasirox have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clarithromycin belongs to Anti Bacterial; Deferasirox belongs to Miscellaneous.
Why it happens
Deferasirox may modestly induce CYP3A4, increasing clarithromycin metabolism.
What to do
Monitor clinical response to the antibiotic and consider an alternative if the infection responds poorly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clarithromycin
- Astemizole + Clarithromycin Contraindicated
- Avanafil + Clarithromycin Contraindicated
- Cisapride + Clarithromycin Contraindicated
- Clarithromycin + Colchicine Contraindicated
- Clarithromycin + Conivaptan Contraindicated
- Clarithromycin + Dihydroergotamine Contraindicated
Other interactions of Deferasirox
Frequently asked questions
Can I take Clarithromycin with Deferasirox?
MediHelp rates the interaction as minor. Clarithromycin and Deferasirox have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may lower clarithromycin concentrations, possibly reducing antibacterial effectiveness. The effect is predicted from weak CYP3A4 induction and is probably small.
How serious is the interaction between Clarithromycin and Deferasirox?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to the antibiotic and consider an alternative if the infection responds poorly.
What other medicines interact with Clarithromycin?
MediHelp also lists interactions of Clarithromycin with, for example, Astemizole, Avanafil, Cisapride. The full list is on the Clarithromycin page.
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