Drug interactions
Clemastine + Lurasidone
Severity: Moderate
Clemastine and Lurasidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Clemastine is a sedating antihistamine with anticholinergic properties. Together with lurasidone it may increase drowsiness and impair alertness.
What this interaction means in plain words
Clemastine and Lurasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Clemastine belongs to Respiratory; Lurasidone belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Monitor for sedation and anticholinergic effects. Prefer a non-sedating antihistamine if suitable.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Other interactions of Clemastine
Frequently asked questions
Can I take Clemastine with Lurasidone?
MediHelp rates the interaction as moderate. Clemastine and Lurasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Clemastine is a sedating antihistamine with anticholinergic properties. Together with lurasidone it may increase drowsiness and impair alertness.
How serious is the interaction between Clemastine and Lurasidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation and anticholinergic effects. Prefer a non-sedating antihistamine if suitable.
What other medicines interact with Lurasidone?
MediHelp also lists interactions of Lurasidone with, for example, Apalutamide, Atazanavir, Carbamazepine. The full list is on the Lurasidone page.
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