Drug interactions
Clomipramine + Motherwort
Severity: Minor
Clomipramine and Motherwort: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Motherwort is traditionally regarded as a mild sedative, so it may add to clomipramine drowsiness. Evidence is based on traditional use and theory rather than clinical studies.
What this interaction means in plain words
Clomipramine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive sedation; the mechanism of motherwort is not well established.
What to do
Advise caution with driving and watch for increased drowsiness. Stop motherwort if sedation becomes troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Clomipramine and Motherwort, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Clomipramine
- Arsenic trioxide + Clomipramine Contraindicated
- Clomipramine + Dofetilide Contraindicated
- Clomipramine + Droperidol Contraindicated
- Clomipramine + Isocarboxazid Contraindicated
- Clomipramine + Methylene blue Contraindicated
- Clomipramine + Pentamidine Contraindicated
Frequently asked questions
Can I take Clomipramine with Motherwort?
MediHelp rates the interaction as minor. Clomipramine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort is traditionally regarded as a mild sedative, so it may add to clomipramine drowsiness. Evidence is based on traditional use and theory rather than clinical studies.
How serious is the interaction between Clomipramine and Motherwort?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise caution with driving and watch for increased drowsiness. Stop motherwort if sedation becomes troublesome.
What other medicines interact with Clomipramine?
MediHelp also lists interactions of Clomipramine with, for example, Arsenic trioxide, Dofetilide, Droperidol. The full list is on the Clomipramine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
