Drug interactions
Clomipramine + Sage
Severity: Minor
Clomipramine and Sage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sage is reported to have mild sedative properties, which could add to the sedation caused by clomipramine. Clinical evidence is scant and the effect is likely small.
What this interaction means in plain words
Clomipramine and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive central nervous system depressant effects.
What to do
Advise patients to watch for excess drowsiness and to take care when driving. Reduce or stop the herbal product if sedation becomes troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clomipramine
- Arsenic trioxide + Clomipramine Contraindicated
- Clomipramine + Dofetilide Contraindicated
- Clomipramine + Droperidol Contraindicated
- Clomipramine + Isocarboxazid Contraindicated
- Clomipramine + Methylene blue Contraindicated
- Clomipramine + Pentamidine Contraindicated
Frequently asked questions
Can I take Clomipramine with Sage?
MediHelp rates the interaction as minor. Clomipramine and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage is reported to have mild sedative properties, which could add to the sedation caused by clomipramine. Clinical evidence is scant and the effect is likely small.
How serious is the interaction between Clomipramine and Sage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for excess drowsiness and to take care when driving. Reduce or stop the herbal product if sedation becomes troublesome.
What other medicines interact with Clomipramine?
MediHelp also lists interactions of Clomipramine with, for example, Arsenic trioxide, Dofetilide, Droperidol. The full list is on the Clomipramine page.
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