Drug interactions
Clonidine + Teduglutide
Severity: Minor
Clonidine and Teduglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide improves intestinal fluid and nutrient absorption and may increase absorption of orally administered drugs. For clonidine, increased exposure could amplify hypotension, bradycardia and sedation, although the effect is not well quantified.
What this interaction means in plain words
Clonidine and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Clonidine belongs to Cardiovascular; Teduglutide belongs to Endocrine.
Why it happens
Enhanced intestinal absorption of oral drugs due to teduglutide's intestinotrophic and fluid-absorption effects.
What to do
Monitor blood pressure and heart rate after starting teduglutide and reduce the clonidine dose if hypotension or bradycardia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clonidine
- Acebutolol + Clonidine Major
- Amifostine + Clonidine Major
- Amiodarone + Clonidine Major
- Amoxapine + Clonidine Major
- Atenolol-chlorthalidone + Clonidine Major
- Atenolol + Clonidine Major
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Clonidine with Teduglutide?
MediHelp rates the interaction as minor. Clonidine and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teduglutide improves intestinal fluid and nutrient absorption and may increase absorption of orally administered drugs. For clonidine, increased exposure could amplify hypotension, bradycardia and sedation, although the effect is not well quantified.
How serious is the interaction between Clonidine and Teduglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate after starting teduglutide and reduce the clonidine dose if hypotension or bradycardia develops.
What other medicines interact with Clonidine?
MediHelp also lists interactions of Clonidine with, for example, Acebutolol, Amifostine, Amiodarone. The full list is on the Clonidine page.
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