Drug interactions
Cyclosporin + Teduglutide
Severity: Moderate
Cyclosporin and Teduglutide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide enhances intestinal fluid absorption and may increase absorption of oral drugs. Cyclosporine, which has a narrow therapeutic index, may reach higher concentrations.
What this interaction means in plain words
Cyclosporin and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cyclosporin belongs to Miscellaneous; Teduglutide belongs to Endocrine.
Why it happens
Improved intestinal absorptive function increases oral drug uptake.
What to do
Monitor cyclosporine trough concentrations when starting or stopping teduglutide. Adjust the dose according to levels.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
- Flecainide + Teduglutide Moderate
Frequently asked questions
Can I take Cyclosporin with Teduglutide?
MediHelp rates the interaction as moderate. Cyclosporin and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teduglutide enhances intestinal fluid absorption and may increase absorption of oral drugs. Cyclosporine, which has a narrow therapeutic index, may reach higher concentrations.
How serious is the interaction between Cyclosporin and Teduglutide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor cyclosporine trough concentrations when starting or stopping teduglutide. Adjust the dose according to levels.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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