Drug interactions
Clorazepate + Sage
Severity: Minor
Clorazepate and Sage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sage is a herbal product with possible mild sedative properties, but clinical evidence of an interaction is limited. Any additive drowsiness with clorazepate is probably minor.
What this interaction means in plain words
Clorazepate and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; the mechanism is not well established.
What to do
No specific action is needed beyond advising patients to report excess drowsiness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Clorazepate
- Calcium / magnesium / potassium / sodium oxybates + Clorazepate Contraindicated
- Clorazepate + Sodium oxybate Contraindicated
- Alfentanil + Clorazepate Major
- Alprazolam + Clorazepate Major
- Amobarbital + Clorazepate Major
- Belladonna and opium + Clorazepate Major
Frequently asked questions
Can I take Clorazepate with Sage?
MediHelp rates the interaction as minor. Clorazepate and Sage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sage is a herbal product with possible mild sedative properties, but clinical evidence of an interaction is limited. Any additive drowsiness with clorazepate is probably minor.
How serious is the interaction between Clorazepate and Sage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond advising patients to report excess drowsiness.
What other medicines interact with Clorazepate?
MediHelp also lists interactions of Clorazepate with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Clorazepate page.
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