Drug interactions
Colestipol + Deflazacort
Severity: Minor
Colestipol and Deflazacort: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Colestipol is a bile acid sequestrant that can bind oral drugs in the gut and reduce their absorption. Taken together, it may lower deflazacort exposure and weaken its anti-inflammatory effect.
What this interaction means in plain words
Colestipol and Deflazacort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Colestipol belongs to Cardiovascular; Deflazacort belongs to Miscellaneous.
Why it happens
Colestipol binds deflazacort in the gastrointestinal lumen, reducing its oral absorption.
What to do
Give deflazacort at least 1 hour before or 4 hours after colestipol. Monitor clinical response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Other interactions of Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderate
- Atenolol-chlorthalidone + Colestipol Moderate
- Azilsartan-chlorthalidone + Colestipol Moderate
- Candesartan-hydrochlorothiazide + Colestipol Moderate
- Captopril-hydrochlorothiazide + Colestipol Moderate
Frequently asked questions
Can I take Colestipol with Deflazacort?
MediHelp rates the interaction as minor. Colestipol and Deflazacort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Colestipol is a bile acid sequestrant that can bind oral drugs in the gut and reduce their absorption. Taken together, it may lower deflazacort exposure and weaken its anti-inflammatory effect.
How serious is the interaction between Colestipol and Deflazacort?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give deflazacort at least 1 hour before or 4 hours after colestipol. Monitor clinical response.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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