Drug interactions
Colestipol + Oxacillin
Severity: Minor
Colestipol and Oxacillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Colestipol is a bile acid sequestrant that can bind other oral drugs in the gut and reduce their absorption. Oral oxacillin may therefore reach lower blood levels if taken at the same time. The clinical impact is probably small but could matter in serious infections.
What this interaction means in plain words
Colestipol and Oxacillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Colestipol belongs to Cardiovascular; Oxacillin belongs to Anti Bacterial.
Why it happens
Binding of oral oxacillin in the gastrointestinal tract by colestipol, reducing absorption.
What to do
Give oral oxacillin at least 1 hour before or 4 hours after colestipol. Intravenous oxacillin is not affected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxacillin
- Bcg vaccine live + Oxacillin Moderate
- Chloramphenicol + Oxacillin Moderate
- Cholera vaccine + Oxacillin Moderate
- Demeclocycline + Oxacillin Moderate
- Doxycycline + Oxacillin Moderate
- Microbiota + Oxacillin Moderate
Other interactions of Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderate
- Atenolol-chlorthalidone + Colestipol Moderate
- Azilsartan-chlorthalidone + Colestipol Moderate
- Candesartan-hydrochlorothiazide + Colestipol Moderate
- Captopril-hydrochlorothiazide + Colestipol Moderate
Frequently asked questions
Can I take Colestipol with Oxacillin?
MediHelp rates the interaction as minor. Colestipol and Oxacillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Colestipol is a bile acid sequestrant that can bind other oral drugs in the gut and reduce their absorption. Oral oxacillin may therefore reach lower blood levels if taken at the same time. The clinical impact is probably small but could matter in serious infections.
How serious is the interaction between Colestipol and Oxacillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral oxacillin at least 1 hour before or 4 hours after colestipol. Intravenous oxacillin is not affected.
What other medicines interact with Oxacillin?
MediHelp also lists interactions of Oxacillin with, for example, Bcg vaccine live, Chloramphenicol, Cholera vaccine. The full list is on the Oxacillin page.
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