Drug interactions
Conivaptan + Etonogestrel
Severity: Minor
Conivaptan and Etonogestrel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Conivaptan inhibits CYP3A4 and could raise etonogestrel levels. Because conivaptan is given only briefly in hospital, any clinical consequence is likely to be small.
What this interaction means in plain words
Conivaptan and Etonogestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of CYP3A4 metabolism of etonogestrel by conivaptan.
What to do
No change is normally needed; be aware of possible transient progestogenic effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Etonogestrel
Frequently asked questions
Can I take Conivaptan with Etonogestrel?
MediHelp rates the interaction as minor. Conivaptan and Etonogestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Conivaptan inhibits CYP3A4 and could raise etonogestrel levels. Because conivaptan is given only briefly in hospital, any clinical consequence is likely to be small.
How serious is the interaction between Conivaptan and Etonogestrel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is normally needed; be aware of possible transient progestogenic effects.
What other medicines interact with Etonogestrel?
MediHelp also lists interactions of Etonogestrel with, for example, Amobarbital, Armodafinil, Bosentan. The full list is on the Etonogestrel page.
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