Drug interactions
Cortisone + Dapsone
Severity: Minor
Cortisone and Dapsone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may weakly induce CYP3A4, which could slightly reduce dapsone exposure. Clinical relevance is doubtful and no meaningful loss of effect is well documented.
What this interaction means in plain words
Cortisone and Dapsone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Cortisone may weakly induce CYP3A4, modestly increasing dapsone metabolism.
What to do
No routine action is required. Review dapsone response if efficacy appears reduced.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapsone
- Bcg vaccine live + Dapsone Major
- Dapsone + Primaquine Major
- Apalutamide + Dapsone Moderate
- Belzutifan + Dapsone Moderate
- Bosentan + Dapsone Moderate
- Bupivacaine implant + Dapsone Moderate
Frequently asked questions
Can I take Cortisone with Dapsone?
MediHelp rates the interaction as minor. Cortisone and Dapsone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids may weakly induce CYP3A4, which could slightly reduce dapsone exposure. Clinical relevance is doubtful and no meaningful loss of effect is well documented.
How serious is the interaction between Cortisone and Dapsone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is required. Review dapsone response if efficacy appears reduced.
What other medicines interact with Dapsone?
MediHelp also lists interactions of Dapsone with, for example, Bcg vaccine live, Primaquine, Apalutamide. The full list is on the Dapsone page.
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