Drug interactions
Cortisone + Dasatinib
Severity: Minor
Cortisone and Dasatinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cortisone is a corticosteroid with CYP3A4 involvement in its handling, and its effects on dasatinib exposure are not well established. Any change in either drug's levels is likely modest at usual doses.
What this interaction means in plain words
Cortisone and Dasatinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible bidirectional CYP3A4 effects (weak inhibition by dasatinib, weak induction by corticosteroids); not well established.
What to do
No empiric dose change. Monitor leukemia response and steroid-related effects if high or prolonged steroid doses are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Cortisone with Dasatinib?
MediHelp rates the interaction as minor. Cortisone and Dasatinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cortisone is a corticosteroid with CYP3A4 involvement in its handling, and its effects on dasatinib exposure are not well established. Any change in either drug's levels is likely modest at usual doses.
How serious is the interaction between Cortisone and Dasatinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empiric dose change. Monitor leukemia response and steroid-related effects if high or prolonged steroid doses are used.
What other medicines interact with Dasatinib?
MediHelp also lists interactions of Dasatinib with, for example, Saquinavir, Thioridazine, Adagrasib. The full list is on the Dasatinib page.
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