Drug interactions
Cortisone + Indacaterol-glycopyrronium
Severity: Moderate
Cortisone and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids promote potassium loss, and beta2-agonists can lower serum potassium through intracellular shift. Together hypokalemia may be more pronounced and could provoke arrhythmias in susceptible patients.
What this interaction means in plain words
Cortisone and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from mineralocorticoid-related renal potassium loss and beta2-mediated potassium shift.
What to do
Monitor serum potassium in patients on prolonged or high-dose corticosteroids, especially with other hypokalemic agents. Replace potassium when low.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Frequently asked questions
Can I take Cortisone with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Cortisone and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids promote potassium loss, and beta2-agonists can lower serum potassium through intracellular shift. Together hypokalemia may be more pronounced and could provoke arrhythmias in susceptible patients.
How serious is the interaction between Cortisone and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients on prolonged or high-dose corticosteroids, especially with other hypokalemic agents. Replace potassium when low.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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