Drug interactions
Cosyntropin + Furosemide
Severity: Minor
Cosyntropin and Furosemide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cosyntropin stimulates adrenal steroid release, which can promote potassium loss. With furosemide this could add to electrolyte depletion, but with single diagnostic doses the effect is likely minimal.
What this interaction means in plain words
Cosyntropin and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cosyntropin belongs to Musculoskeletal; Furosemide belongs to Cardiovascular.
Why it happens
Adrenal steroid stimulation causes potassium loss that adds to loop diuretic kaliuresis.
What to do
No action is needed for single diagnostic doses. Monitor potassium if repeated dosing is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Other interactions of Cosyntropin
Frequently asked questions
Can I take Cosyntropin with Furosemide?
MediHelp rates the interaction as minor. Cosyntropin and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cosyntropin stimulates adrenal steroid release, which can promote potassium loss. With furosemide this could add to electrolyte depletion, but with single diagnostic doses the effect is likely minimal.
How serious is the interaction between Cosyntropin and Furosemide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for single diagnostic doses. Monitor potassium if repeated dosing is used.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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