Drug interactions
Cyclosporin + Dulaglutide
Severity: Minor
Cyclosporin and Dulaglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dulaglutide delays gastric emptying, which could alter absorption of oral cyclosporin. Because cyclosporin has a narrow therapeutic index, even small changes in exposure may matter.
What this interaction means in plain words
Cyclosporin and Dulaglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Dulaglutide belongs to Endocrine.
Why it happens
Delayed gastric emptying from GLP-1 receptor agonism may change the rate of cyclosporin absorption.
What to do
Monitor cyclosporin trough concentrations after starting or changing dulaglutide dosing, especially in transplant patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Other interactions of Dulaglutide
Frequently asked questions
Can I take Cyclosporin with Dulaglutide?
MediHelp rates the interaction as minor. Cyclosporin and Dulaglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dulaglutide delays gastric emptying, which could alter absorption of oral cyclosporin. Because cyclosporin has a narrow therapeutic index, even small changes in exposure may matter.
How serious is the interaction between Cyclosporin and Dulaglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor cyclosporin trough concentrations after starting or changing dulaglutide dosing, especially in transplant patients.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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