Drug interactions
Cyclosporin + Teicoplanin
Severity: Moderate
Cyclosporin and Teicoplanin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can injure the kidney and, less commonly, the ear, so combined use may increase the risk of renal impairment and ototoxicity. Cyclosporine's baseline renal effects make this more important.
What this interaction means in plain words
Cyclosporin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cyclosporin belongs to Miscellaneous; Teicoplanin belongs to Anti Bacterial.
Why it happens
Additive nephrotoxicity and potential ototoxicity, via distinct pharmacodynamic effects on renal and cochlear tissue.
What to do
Monitor serum creatinine and cyclosporine trough levels, and teicoplanin trough concentrations in prolonged therapy. Assess hearing if symptoms develop, and reduce doses if renal function declines.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Other interactions of Teicoplanin
- Amphotericin b + Teicoplanin Major
- Cidofovir + Teicoplanin Major
- Neomycin + Teicoplanin Major
- Teicoplanin + Tobramycin Major
- Acyclovir + Teicoplanin Moderate
- Adefovir + Teicoplanin Moderate
Frequently asked questions
Can I take Cyclosporin with Teicoplanin?
MediHelp rates the interaction as moderate. Cyclosporin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can injure the kidney and, less commonly, the ear, so combined use may increase the risk of renal impairment and ototoxicity. Cyclosporine's baseline renal effects make this more important.
How serious is the interaction between Cyclosporin and Teicoplanin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and cyclosporine trough levels, and teicoplanin trough concentrations in prolonged therapy. Assess hearing if symptoms develop, and reduce doses if renal function declines.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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