Drug interactions
Dalteparin + Danshen
Severity: Moderate
Dalteparin and Danshen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danshen (Salvia miltiorrhiza) has antiplatelet and anticoagulant-like properties and has been reported to potentiate warfarin. Combined with dalteparin it may raise the risk of bleeding.
What this interaction means in plain words
Dalteparin and Danshen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effect through inhibition of platelet aggregation and possible effects on coagulation.
What to do
Advise patients to avoid danshen while on dalteparin where possible. If used, monitor for bleeding and bruising and review the need for the herbal product.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Frequently asked questions
Can I take Dalteparin with Danshen?
MediHelp rates the interaction as moderate. Dalteparin and Danshen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Danshen (Salvia miltiorrhiza) has antiplatelet and anticoagulant-like properties and has been reported to potentiate warfarin. Combined with dalteparin it may raise the risk of bleeding.
How serious is the interaction between Dalteparin and Danshen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid danshen while on dalteparin where possible. If used, monitor for bleeding and bruising and review the need for the herbal product.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
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