Drug interactions
Dalteparin + Deferasirox
Severity: Moderate
Dalteparin and Deferasirox: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox is associated with gastrointestinal ulceration and haemorrhage, and may cause thrombocytopenia. Anticoagulation with dalteparin could make such bleeding more likely or more severe.
What this interaction means in plain words
Dalteparin and Deferasirox can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dalteparin belongs to Cardiovascular; Deferasirox belongs to Miscellaneous.
Why it happens
Pharmacodynamic additive bleeding risk from deferasirox GI mucosal injury combined with dalteparin anticoagulation.
What to do
Monitor for GI bleeding, haemoglobin and platelet counts. Stop deferasirox and reassess if GI haemorrhage occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Other interactions of Deferasirox
Frequently asked questions
Can I take Dalteparin with Deferasirox?
MediHelp rates the interaction as moderate. Dalteparin and Deferasirox can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox is associated with gastrointestinal ulceration and haemorrhage, and may cause thrombocytopenia. Anticoagulation with dalteparin could make such bleeding more likely or more severe.
How serious is the interaction between Dalteparin and Deferasirox?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for GI bleeding, haemoglobin and platelet counts. Stop deferasirox and reassess if GI haemorrhage occurs.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
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