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Drug interactions

Dalteparin + Dong quai

Severity: Moderate

Dalteparin and Dong quai: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Dong quai contains coumarin-type constituents and has been linked to antiplatelet effects and raised INR with warfarin. Combined with dalteparin it may increase the risk of bleeding, although data are mostly case-based.

What this interaction means in plain words

Dalteparin and Dong quai can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Coumarin constituents and possible platelet inhibition by dong quai may add to the anticoagulant effect of dalteparin.

What to do

Advise patients to avoid dong quai while on dalteparin. If it is used, monitor for signs of bleeding and check the hemoglobin if symptoms appear.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dalteparin with Dong quai?

MediHelp rates the interaction as moderate. Dalteparin and Dong quai can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type constituents and has been linked to antiplatelet effects and raised INR with warfarin. Combined with dalteparin it may increase the risk of bleeding, although data are mostly case-based.

How serious is the interaction between Dalteparin and Dong quai?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai while on dalteparin. If it is used, monitor for signs of bleeding and check the hemoglobin if symptoms appear.

What other medicines interact with Dalteparin?

MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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