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Drug interactions

Dalteparin + Ethanol

Severity: Moderate

Dalteparin and Ethanol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Heavy or acute alcohol intake impairs platelet function and can injure the gastric mucosa, and so may raise bleeding risk in patients on low-molecular-weight heparin. Intoxication also increases the risk of falls and trauma.

What this interaction means in plain words

Dalteparin and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive pharmacodynamic effects of alcohol on platelet function and mucosal integrity; no direct effect on dalteparin kinetics is established.

What to do

Counsel patients to avoid binge or heavy alcohol use during dalteparin therapy. Monitor for bleeding, especially gastrointestinal, in patients who drink.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dalteparin with Ethanol?

MediHelp rates the interaction as moderate. Dalteparin and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Heavy or acute alcohol intake impairs platelet function and can injure the gastric mucosa, and so may raise bleeding risk in patients on low-molecular-weight heparin. Intoxication also increases the risk of falls and trauma.

How serious is the interaction between Dalteparin and Ethanol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid binge or heavy alcohol use during dalteparin therapy. Monitor for bleeding, especially gastrointestinal, in patients who drink.

What other medicines interact with Dalteparin?

MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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