Drug interactions
Dalteparin + Ethotoin
Severity: Minor
Dalteparin and Ethotoin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydantoin anticonvulsants have shown variable effects on anticoagulant response, mainly with warfarin. Evidence for a meaningful interaction with dalteparin specifically is lacking, and the legacy claim that dalteparin raises ethotoin levels is not supported.
What this interaction means in plain words
Dalteparin and Ethotoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism for LMWH; hydantoin effects on coagulation are described mainly for vitamin K antagonists.
What to do
No routine change is needed. Monitor for bleeding and anticonvulsant response as clinically indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Frequently asked questions
Can I take Dalteparin with Ethotoin?
MediHelp rates the interaction as minor. Dalteparin and Ethotoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydantoin anticonvulsants have shown variable effects on anticoagulant response, mainly with warfarin. Evidence for a meaningful interaction with dalteparin specifically is lacking, and the legacy claim that dalteparin raises ethotoin levels is not supported.
How serious is the interaction between Dalteparin and Ethotoin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor for bleeding and anticonvulsant response as clinically indicated.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
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