Drug interactions
Dalteparin + Feverfew
Severity: Moderate
Dalteparin and Feverfew: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Feverfew inhibits platelet aggregation in laboratory studies and may therefore add to the bleeding risk of dalteparin. Clinical reports of bleeding are scarce.
What this interaction means in plain words
Dalteparin and Feverfew can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Feverfew constituents such as parthenolide inhibit platelet function, adding to dalteparin's anticoagulant effect.
What to do
Advise patients to avoid feverfew products during dalteparin treatment. Monitor for bleeding if they continue.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Frequently asked questions
Can I take Dalteparin with Feverfew?
MediHelp rates the interaction as moderate. Dalteparin and Feverfew can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Feverfew inhibits platelet aggregation in laboratory studies and may therefore add to the bleeding risk of dalteparin. Clinical reports of bleeding are scarce.
How serious is the interaction between Dalteparin and Feverfew?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid feverfew products during dalteparin treatment. Monitor for bleeding if they continue.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
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