Drug interactions
Dalteparin + Icosapent
Severity: Moderate
Dalteparin and Icosapent: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Icosapent ethyl can prolong bleeding time modestly. Combined with dalteparin, bleeding risk may be somewhat increased.
What this interaction means in plain words
Dalteparin and Icosapent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effect of omega-3 antiplatelet activity and anticoagulation.
What to do
Monitor periodically for bleeding when the two are used together. Reassess if bleeding events occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Frequently asked questions
Can I take Dalteparin with Icosapent?
MediHelp rates the interaction as moderate. Dalteparin and Icosapent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Icosapent ethyl can prolong bleeding time modestly. Combined with dalteparin, bleeding risk may be somewhat increased.
How serious is the interaction between Dalteparin and Icosapent?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor periodically for bleeding when the two are used together. Reassess if bleeding events occur.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
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