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Drug interactions

Dalteparin + Omega 3 fatty acids

Severity: Moderate

Dalteparin and Omega 3 fatty acids: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Omega-3 fatty acids at higher doses can reduce platelet aggregation and prolong bleeding time. With dalteparin this may add modestly to bleeding risk.

What this interaction means in plain words

Dalteparin and Omega 3 fatty acids can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Additive pharmacodynamic effect from omega-3 mediated platelet inhibition.

What to do

Monitor for bleeding periodically during combined use. Reassess therapy if bleeding develops.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dalteparin with Omega 3 fatty acids?

MediHelp rates the interaction as moderate. Dalteparin and Omega 3 fatty acids can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Omega-3 fatty acids at higher doses can reduce platelet aggregation and prolong bleeding time. With dalteparin this may add modestly to bleeding risk.

How serious is the interaction between Dalteparin and Omega 3 fatty acids?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding periodically during combined use. Reassess therapy if bleeding develops.

What other medicines interact with Dalteparin?

MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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