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Drug interactions

Dalteparin + Pau d'arco

Severity: Minor

Dalteparin and Pau d'arco: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Pau d'arco contains naphthoquinones such as lapachol, which may have anticoagulant effects through interference with vitamin K. A bleeding interaction with dalteparin is theoretical.

What this interaction means in plain words

Dalteparin and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Lapachol may antagonize vitamin K, possibly adding to anticoagulation; not shown clinically with heparins.

What to do

Advise avoiding pau d'arco products. Monitor for bleeding if used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dalteparin with Pau d'arco?

MediHelp rates the interaction as minor. Dalteparin and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pau d'arco contains naphthoquinones such as lapachol, which may have anticoagulant effects through interference with vitamin K. A bleeding interaction with dalteparin is theoretical.

How serious is the interaction between Dalteparin and Pau d'arco?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding pau d'arco products. Monitor for bleeding if used.

What other medicines interact with Dalteparin?

MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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