Drug interactions
Danazol + Saxagliptin
Severity: Minor
Danazol and Saxagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol may impair glucose tolerance and cause insulin resistance, and it weakly inhibits CYP3A4, so saxagliptin exposure could rise modestly. The net effect is likely small.
What this interaction means in plain words
Danazol and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Androgenic effects on insulin sensitivity plus weak CYP3A4 inhibition by danazol.
What to do
Monitor blood glucose during danazol therapy. Adjust antidiabetic therapy if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Frequently asked questions
Can I take Danazol with Saxagliptin?
MediHelp rates the interaction as minor. Danazol and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol may impair glucose tolerance and cause insulin resistance, and it weakly inhibits CYP3A4, so saxagliptin exposure could rise modestly. The net effect is likely small.
How serious is the interaction between Danazol and Saxagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during danazol therapy. Adjust antidiabetic therapy if control changes.
What other medicines interact with Saxagliptin?
MediHelp also lists interactions of Saxagliptin with, for example, Albiglutide, Amlodipine-benazepril, Aripiprazole. The full list is on the Saxagliptin page.
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