Drug interactions
Dapagliflozin-metformin + Levonorgestrel
Severity: Minor
Dapagliflozin-metformin and Levonorgestrel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levonorgestrel may slightly reduce glucose tolerance in some patients, but emergency or low-dose use rarely affects diabetes control meaningfully.
What this interaction means in plain words
Dapagliflozin-metformin and Levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dapagliflozin-metformin belongs to Endocrine; Levonorgestrel belongs to Endocrine.
Why it happens
Progestogens may modestly reduce insulin sensitivity, giving weak antagonism of antidiabetic effects.
What to do
No routine adjustment is needed; monitor glucose if used long term and adjust antidiabetic therapy only if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Other interactions of Levonorgestrel
Frequently asked questions
Can I take Dapagliflozin-metformin with Levonorgestrel?
MediHelp rates the interaction as minor. Dapagliflozin-metformin and Levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levonorgestrel may slightly reduce glucose tolerance in some patients, but emergency or low-dose use rarely affects diabetes control meaningfully.
How serious is the interaction between Dapagliflozin-metformin and Levonorgestrel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; monitor glucose if used long term and adjust antidiabetic therapy only if control worsens.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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