Drug interactions
Dapsone + Ethanol
Severity: Minor
Dapsone and Ethanol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chronic alcohol use may induce CYP2E1 and slightly increase dapsone clearance. The effect is small and of uncertain clinical significance.
What this interaction means in plain words
Dapsone and Ethanol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Ethanol induces CYP2E1, which may marginally enhance dapsone metabolism.
What to do
No dose change is usually required. Counsel on alcohol use given the risk of hepatotoxicity with both.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapsone
- Bcg vaccine live + Dapsone Major
- Dapsone + Primaquine Major
- Apalutamide + Dapsone Moderate
- Belzutifan + Dapsone Moderate
- Bosentan + Dapsone Moderate
- Bupivacaine implant + Dapsone Moderate
Frequently asked questions
Can I take Dapsone with Ethanol?
MediHelp rates the interaction as minor. Dapsone and Ethanol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chronic alcohol use may induce CYP2E1 and slightly increase dapsone clearance. The effect is small and of uncertain clinical significance.
How serious is the interaction between Dapsone and Ethanol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually required. Counsel on alcohol use given the risk of hepatotoxicity with both.
What other medicines interact with Dapsone?
MediHelp also lists interactions of Dapsone with, for example, Bcg vaccine live, Primaquine, Apalutamide. The full list is on the Dapsone page.
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