Drug interactions
Darolutamide + Dipyridamole
Severity: Minor
Darolutamide and Dipyridamole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Darolutamide inhibits BCRP in vitro and may increase exposure to BCRP substrates. Dipyridamole is not a well-established BCRP substrate with a narrow therapeutic range, so the effect is likely small.
What this interaction means in plain words
Darolutamide and Dipyridamole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Darolutamide belongs to Miscellaneous; Dipyridamole belongs to Cardiovascular.
Why it happens
Darolutamide inhibits BCRP, potentially reducing efflux of dipyridamole.
What to do
No routine action is needed; be aware of enhanced dipyridamole effects such as headache or hypotension.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Darolutamide
Frequently asked questions
Can I take Darolutamide with Dipyridamole?
MediHelp rates the interaction as minor. Darolutamide and Dipyridamole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Darolutamide inhibits BCRP in vitro and may increase exposure to BCRP substrates. Dipyridamole is not a well-established BCRP substrate with a narrow therapeutic range, so the effect is likely small.
How serious is the interaction between Darolutamide and Dipyridamole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; be aware of enhanced dipyridamole effects such as headache or hypotension.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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