Drug interactions
Dasatinib + Estrogens esterified
Severity: Minor
Dasatinib and Estrogens esterified: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib may weakly inhibit CYP3A4 and slightly raise estrogen exposure. The clinical effect is expected to be small.
What this interaction means in plain words
Dasatinib and Estrogens esterified have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak CYP3A4 inhibition by dasatinib reduces estrogen metabolism.
What to do
No dose adjustment is usually needed. Monitor for breast tenderness or bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Estrogens esterified?
MediHelp rates the interaction as minor. Dasatinib and Estrogens esterified have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dasatinib may weakly inhibit CYP3A4 and slightly raise estrogen exposure. The clinical effect is expected to be small.
How serious is the interaction between Dasatinib and Estrogens esterified?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed. Monitor for breast tenderness or bleeding.
What other medicines interact with Dasatinib?
MediHelp also lists interactions of Dasatinib with, for example, Saquinavir, Thioridazine, Adagrasib. The full list is on the Dasatinib page.
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