Drug interactions
Dasatinib + Ethinylestradiol
Severity: Minor
Dasatinib and Ethinylestradiol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ethinylestradiol is a weak CYP3A4 inhibitor and may slightly raise dasatinib exposure. Dasatinib may also modestly raise estrogen levels. Effects are likely small.
What this interaction means in plain words
Dasatinib and Ethinylestradiol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak mutual CYP3A4 inhibition.
What to do
No routine adjustment. Monitor for dasatinib adverse effects and estrogenic effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Ethinylestradiol?
MediHelp rates the interaction as minor. Dasatinib and Ethinylestradiol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ethinylestradiol is a weak CYP3A4 inhibitor and may slightly raise dasatinib exposure. Dasatinib may also modestly raise estrogen levels. Effects are likely small.
How serious is the interaction between Dasatinib and Ethinylestradiol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment. Monitor for dasatinib adverse effects and estrogenic effects.
What other medicines interact with Dasatinib?
MediHelp also lists interactions of Dasatinib with, for example, Saquinavir, Thioridazine, Adagrasib. The full list is on the Dasatinib page.
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