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Drug interactions

Dasatinib + Formoterol

Severity: Moderate

Dasatinib and Formoterol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Dasatinib can prolong the QT interval, and high doses of formoterol may also affect QTc and provoke tachycardia and hypokalemia. Together they may modestly increase the risk of ventricular arrhythmia, particularly with electrolyte disturbance or pre-existing cardiac disease.

What this interaction means in plain words

Dasatinib and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Dasatinib belongs to Oncology; Formoterol belongs to Respiratory.

Evidence level: Low

Why it happens

Additive QT prolongation, with formoterol-induced hypokalemia potentially adding to arrhythmic risk.

What to do

Correct potassium and magnesium before and during therapy and obtain a baseline ECG, repeating it if symptoms or other QT-prolonging drugs are added.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dasatinib with Formoterol?

MediHelp rates the interaction as moderate. Dasatinib and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dasatinib can prolong the QT interval, and high doses of formoterol may also affect QTc and provoke tachycardia and hypokalemia. Together they may modestly increase the risk of ventricular arrhythmia, particularly with electrolyte disturbance or pre-existing cardiac disease.

How serious is the interaction between Dasatinib and Formoterol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct potassium and magnesium before and during therapy and obtain a baseline ECG, repeating it if symptoms or other QT-prolonging drugs are added.

What other medicines interact with Formoterol?

MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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