Drug interactions
Dasatinib + Promazine
Severity: Moderate
Dasatinib and Promazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents may prolong the QTc interval; phenothiazines are associated with torsades de pointes. Combined use increases arrhythmia risk.
What this interaction means in plain words
Dasatinib and Promazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Monitor ECG and correct electrolytes, or choose an antipsychotic with less QT effect.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Promazine?
MediHelp rates the interaction as moderate. Dasatinib and Promazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents may prolong the QTc interval; phenothiazines are associated with torsades de pointes. Combined use increases arrhythmia risk.
How serious is the interaction between Dasatinib and Promazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct electrolytes, or choose an antipsychotic with less QT effect.
What other medicines interact with Dasatinib?
MediHelp also lists interactions of Dasatinib with, for example, Saquinavir, Thioridazine, Adagrasib. The full list is on the Dasatinib page.
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