Drug interactions
Dasatinib + Vilanterol / fluticasone furoate inhaled
Severity: Moderate
Dasatinib and Vilanterol / fluticasone furoate inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vilanterol can prolong the QT interval and cause tachycardia, and dasatinib may add to QT effects. Systemic exposure from inhalation is low, so the risk is modest but greater in patients with cardiac disease.
What this interaction means in plain words
Dasatinib and Vilanterol / fluticasone furoate inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta-adrenergic cardiac effects.
What to do
Use only at the labeled inhaler dose, with baseline ECG in patients with cardiac risk factors. Correct hypokalemia and monitor for palpitations.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Vilanterol / fluticasone furoate inhaled?
MediHelp rates the interaction as moderate. Dasatinib and Vilanterol / fluticasone furoate inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vilanterol can prolong the QT interval and cause tachycardia, and dasatinib may add to QT effects. Systemic exposure from inhalation is low, so the risk is modest but greater in patients with cardiac disease.
How serious is the interaction between Dasatinib and Vilanterol / fluticasone furoate inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only at the labeled inhaler dose, with baseline ECG in patients with cardiac risk factors. Correct hypokalemia and monitor for palpitations.
What other medicines interact with Dasatinib?
MediHelp also lists interactions of Dasatinib with, for example, Saquinavir, Thioridazine, Adagrasib. The full list is on the Dasatinib page.
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