Drug interactions
Deferasirox + Dronedarone
Severity: Minor
Deferasirox and Dronedarone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may modestly reduce dronedarone levels, which could weaken its antiarrhythmic effect. The evidence is limited.
What this interaction means in plain words
Deferasirox and Dronedarone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deferasirox belongs to Miscellaneous; Dronedarone belongs to Cardiovascular.
Why it happens
Deferasirox may induce CYP3A4 and increase dronedarone metabolism, although it also inhibits CYP2C8 and CYP1A2, so the net effect is uncertain.
What to do
Monitor rhythm control and ECG; no routine dose adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Deferasirox and Dronedarone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Dronedarone
- Adagrasib + Dronedarone Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Arsenic trioxide + Dronedarone Contraindicated
- Artemether / lumefantrine + Dronedarone Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Azithromycin + Dronedarone Contraindicated
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Dronedarone?
MediHelp rates the interaction as minor. Deferasirox and Dronedarone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may modestly reduce dronedarone levels, which could weaken its antiarrhythmic effect. The evidence is limited.
How serious is the interaction between Deferasirox and Dronedarone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor rhythm control and ECG; no routine dose adjustment is needed.
What other medicines interact with Dronedarone?
MediHelp also lists interactions of Dronedarone with, for example, Adagrasib, Amiodarone, Arsenic trioxide. The full list is on the Dronedarone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
