Drug interactions
Deferiprone + Levetiracetam
Severity: Moderate
Deferiprone and Levetiracetam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferiprone can cause neutropenia and agranulocytosis, and levetiracetam has rarely been associated with hematologic suppression. Using them together may add to the risk of low neutrophil counts and serious infection.
What this interaction means in plain words
Deferiprone and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferiprone belongs to Miscellaneous; Levetiracetam belongs to Central Nervous System.
Why it happens
Additive potential for bone marrow suppression and neutropenia.
What to do
Monitor absolute neutrophil count more often than usual and counsel the patient to report fever or infection symptoms promptly. Interrupt deferiprone if neutropenia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levetiracetam
Other interactions of Deferiprone
- Clozapine + Deferiprone Contraindicated
- Abemaciclib + Deferiprone Major
- Acalabrutinib + Deferiprone Major
- Ado-trastuzumab emtansine + Deferiprone Major
- Ado-trastuzumab + Deferiprone Major
- Aldesleukin + Deferiprone Major
Frequently asked questions
Can I take Deferiprone with Levetiracetam?
MediHelp rates the interaction as moderate. Deferiprone and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferiprone can cause neutropenia and agranulocytosis, and levetiracetam has rarely been associated with hematologic suppression. Using them together may add to the risk of low neutrophil counts and serious infection.
How serious is the interaction between Deferiprone and Levetiracetam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor absolute neutrophil count more often than usual and counsel the patient to report fever or infection symptoms promptly. Interrupt deferiprone if neutropenia develops.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
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