Drug interactions
Deflazacort + Formoterol-mometasone
Severity: Moderate
Deflazacort and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Formoterol and systemic corticosteroids such as deflazacort can each lower serum potassium. Together, particularly at higher doses or in patients with other risk factors, hypokalemia may be additive and predispose to arrhythmias.
What this interaction means in plain words
Deflazacort and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive hypokalemia through beta-2 agonist-driven intracellular potassium shift and corticosteroid-related renal potassium loss.
What to do
Monitor serum potassium in patients on regular formoterol and deflazacort, especially with diuretics or in severe asthma/COPD. Replace potassium if low.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Deflazacort with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Deflazacort and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Formoterol and systemic corticosteroids such as deflazacort can each lower serum potassium. Together, particularly at higher doses or in patients with other risk factors, hypokalemia may be additive and predispose to arrhythmias.
How serious is the interaction between Deflazacort and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients on regular formoterol and deflazacort, especially with diuretics or in severe asthma/COPD. Replace potassium if low.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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