Drug interactions
Degarelix + Formoterol-mometasone
Severity: Moderate
Degarelix and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Degarelix, like other androgen deprivation therapy, may prolong the QT interval, and formoterol can also prolong QTc at higher doses. Combined use may increase the risk of QT-related arrhythmias, especially with electrolyte disturbances.
What this interaction means in plain words
Degarelix and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Degarelix belongs to Endocrine; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT prolongation through different pharmacodynamic mechanisms.
What to do
Check baseline ECG and electrolytes in patients with cardiac risk factors and correct potassium and magnesium. Avoid exceeding recommended formoterol doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Degarelix
- Degarelix + Pimozide Contraindicated
- Degarelix + Thioridazine Contraindicated
- Amiodarone + Degarelix Major
- Amisulpride + Degarelix Major
- Anagrelide + Degarelix Major
- Cisapride + Degarelix Major
Frequently asked questions
Can I take Degarelix with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Degarelix and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Degarelix, like other androgen deprivation therapy, may prolong the QT interval, and formoterol can also prolong QTc at higher doses. Combined use may increase the risk of QT-related arrhythmias, especially with electrolyte disturbances.
How serious is the interaction between Degarelix and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with cardiac risk factors and correct potassium and magnesium. Avoid exceeding recommended formoterol doses.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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