Drug interactions
Degarelix + Ipratropium-salbutamol
Severity: Moderate
Degarelix and Ipratropium-salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Degarelix, like other androgen deprivation therapy, may prolong the QT interval. Salbutamol can add to this through tachycardia and hypokalemia, particularly at high doses.
What this interaction means in plain words
Degarelix and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Degarelix belongs to Endocrine; Ipratropium-salbutamol belongs to Respiratory.
Why it happens
Additive QT prolongation, with possible beta-2 agonist-induced hypokalemia.
What to do
Monitor ECG and electrolytes in patients with cardiac risk factors or heavy salbutamol use. Correct potassium and magnesium abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Degarelix
- Degarelix + Pimozide Contraindicated
- Degarelix + Thioridazine Contraindicated
- Amiodarone + Degarelix Major
- Amisulpride + Degarelix Major
- Anagrelide + Degarelix Major
- Cisapride + Degarelix Major
Frequently asked questions
Can I take Degarelix with Ipratropium-salbutamol?
MediHelp rates the interaction as moderate. Degarelix and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Degarelix, like other androgen deprivation therapy, may prolong the QT interval. Salbutamol can add to this through tachycardia and hypokalemia, particularly at high doses.
How serious is the interaction between Degarelix and Ipratropium-salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes in patients with cardiac risk factors or heavy salbutamol use. Correct potassium and magnesium abnormalities.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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