Drug interactions
Degarelix + Umeclidinium-vilanterol
Severity: Minor
Degarelix and Umeclidinium-vilanterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Degarelix, like other androgen deprivation therapy, may prolong the QT interval. Vilanterol adds beta-adrenergic cardiac effects, so combined use may slightly increase arrhythmia risk in patients with cardiac disease.
What this interaction means in plain words
Degarelix and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Degarelix belongs to Endocrine; Umeclidinium-vilanterol belongs to Respiratory.
Why it happens
Possible additive QT prolongation and beta-agonist cardiac stimulation.
What to do
Awareness is generally sufficient. Obtain an ECG and check electrolytes in patients with known QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Umeclidinium-vilanterol
Other interactions of Degarelix
- Degarelix + Pimozide Contraindicated
- Degarelix + Thioridazine Contraindicated
- Amiodarone + Degarelix Major
- Amisulpride + Degarelix Major
- Anagrelide + Degarelix Major
- Cisapride + Degarelix Major
Frequently asked questions
Can I take Degarelix with Umeclidinium-vilanterol?
MediHelp rates the interaction as minor. Degarelix and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Degarelix, like other androgen deprivation therapy, may prolong the QT interval. Vilanterol adds beta-adrenergic cardiac effects, so combined use may slightly increase arrhythmia risk in patients with cardiac disease.
How serious is the interaction between Degarelix and Umeclidinium-vilanterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Awareness is generally sufficient. Obtain an ECG and check electrolytes in patients with known QT risk factors.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
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