Drug interactions
Deutetrabenazine + Eribulin
Severity: Moderate
Deutetrabenazine and Eribulin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eribulin prolongs QT, and deutetrabenazine may add a small effect, particularly with risk factors. The combined risk of torsades de pointes is modest but real.
What this interaction means in plain words
Deutetrabenazine and Eribulin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deutetrabenazine belongs to Central Nervous System; Eribulin belongs to Oncology.
Why it happens
Additive QT interval prolongation.
What to do
Obtain baseline ECG and monitor electrolytes, correcting hypokalemia and hypomagnesemia. Be careful in patients with bradycardia or congenital long QT.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eribulin
Other interactions of Deutetrabenazine
- Deutetrabenazine + Isocarboxazid Contraindicated
- Deutetrabenazine + Linezolid Contraindicated
- Deutetrabenazine + Phenelzine Contraindicated
- Deutetrabenazine + Rasagiline Contraindicated
- Deutetrabenazine + Safinamide Contraindicated
- Deutetrabenazine + Selegiline Contraindicated
Frequently asked questions
Can I take Deutetrabenazine with Eribulin?
MediHelp rates the interaction as moderate. Deutetrabenazine and Eribulin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin prolongs QT, and deutetrabenazine may add a small effect, particularly with risk factors. The combined risk of torsades de pointes is modest but real.
How serious is the interaction between Deutetrabenazine and Eribulin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain baseline ECG and monitor electrolytes, correcting hypokalemia and hypomagnesemia. Be careful in patients with bradycardia or congenital long QT.
What other medicines interact with Eribulin?
MediHelp also lists interactions of Eribulin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Eribulin page.
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