Drug interactions
Deutetrabenazine + Foscarnet
Severity: Moderate
Deutetrabenazine and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Foscarnet can prolong the QT interval and disturb calcium, magnesium and potassium. Deutetrabenazine has a small QT effect at usual doses, but electrolyte disturbance or other risk factors could raise the risk of torsade de pointes.
What this interaction means in plain words
Deutetrabenazine and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deutetrabenazine belongs to Central Nervous System; Foscarnet belongs to Anti Virals.
Why it happens
Additive QT prolongation with foscarnet-related electrolyte disturbances.
What to do
Obtain a baseline ECG and monitor it with serum electrolytes, correcting hypokalemia, hypomagnesemia and hypocalcemia. Avoid the combination in patients with congenital long QT.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Deutetrabenazine
- Deutetrabenazine + Isocarboxazid Contraindicated
- Deutetrabenazine + Linezolid Contraindicated
- Deutetrabenazine + Phenelzine Contraindicated
- Deutetrabenazine + Rasagiline Contraindicated
- Deutetrabenazine + Safinamide Contraindicated
- Deutetrabenazine + Selegiline Contraindicated
Frequently asked questions
Can I take Deutetrabenazine with Foscarnet?
MediHelp rates the interaction as moderate. Deutetrabenazine and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Foscarnet can prolong the QT interval and disturb calcium, magnesium and potassium. Deutetrabenazine has a small QT effect at usual doses, but electrolyte disturbance or other risk factors could raise the risk of torsade de pointes.
How serious is the interaction between Deutetrabenazine and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor it with serum electrolytes, correcting hypokalemia, hypomagnesemia and hypocalcemia. Avoid the combination in patients with congenital long QT.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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