Drug interactions
Deutetrabenazine + Sunitinib
Severity: Minor
Deutetrabenazine and Sunitinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sunitinib can prolong the QT interval, while deutetrabenazine has little QT effect at recommended doses. Risk is small but may increase in patients with bradycardia, electrolyte disturbances or other QT-prolonging drugs.
What this interaction means in plain words
Deutetrabenazine and Sunitinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deutetrabenazine belongs to Central Nervous System; Sunitinib belongs to Oncology.
Why it happens
Possible additive QT prolongation, although deutetrabenazine's own effect is small at recommended doses.
What to do
Check baseline ECG and electrolytes in patients with additional QT risk factors. Correct potassium and magnesium abnormalities.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sunitinib
- Adagrasib + Sunitinib Major
- Amiodarone + Sunitinib Major
- Amisulpride + Sunitinib Major
- Anagrelide + Sunitinib Major
- Apalutamide + Sunitinib Major
- Arsenic trioxide + Sunitinib Major
Other interactions of Deutetrabenazine
- Deutetrabenazine + Isocarboxazid Contraindicated
- Deutetrabenazine + Linezolid Contraindicated
- Deutetrabenazine + Phenelzine Contraindicated
- Deutetrabenazine + Rasagiline Contraindicated
- Deutetrabenazine + Safinamide Contraindicated
- Deutetrabenazine + Selegiline Contraindicated
Frequently asked questions
Can I take Deutetrabenazine with Sunitinib?
MediHelp rates the interaction as minor. Deutetrabenazine and Sunitinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sunitinib can prolong the QT interval, while deutetrabenazine has little QT effect at recommended doses. Risk is small but may increase in patients with bradycardia, electrolyte disturbances or other QT-prolonging drugs.
How serious is the interaction between Deutetrabenazine and Sunitinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with additional QT risk factors. Correct potassium and magnesium abnormalities.
What other medicines interact with Sunitinib?
MediHelp also lists interactions of Sunitinib with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Sunitinib page.
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