Drug interactions
Devil's claw + Fondaparinux
Severity: Minor
Devil's claw and Fondaparinux: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw has been linked to antiplatelet activity and isolated bleeding reports, mostly with warfarin. Use with fondaparinux could theoretically add to bleeding risk.
What this interaction means in plain words
Devil's claw and Fondaparinux have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak antiplatelet effect adding to anticoagulation; mechanism not firmly established.
What to do
Ask patients about herbal use and advise avoiding devil's claw during anticoagulation, or monitor for bruising and bleeding if it is continued.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Frequently asked questions
Can I take Devil's claw with Fondaparinux?
MediHelp rates the interaction as minor. Devil's claw and Fondaparinux have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw has been linked to antiplatelet activity and isolated bleeding reports, mostly with warfarin. Use with fondaparinux could theoretically add to bleeding risk.
How serious is the interaction between Devil's claw and Fondaparinux?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise avoiding devil's claw during anticoagulation, or monitor for bruising and bleeding if it is continued.
What other medicines interact with Fondaparinux?
MediHelp also lists interactions of Fondaparinux with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Fondaparinux page.
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